What Is CBD/cbg Hemp Oil

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CBG vs CBD: Detailed Breakdown and Best Products While there's no doubt that CBD has become a hot topic in health and wellness, there's a new cannabinoid making a notable impression in the scene—CBG. We're calling it a "new" cannabinoid, but it's not technically new. CBG is only now taking center stage in pharmacological studies and making a splash in cannabis produc

CBG vs CBD: Detailed Breakdown and Best Products

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CBD and THC are definitely two of the most well-known cannabinoids. CBD is known for its calming, therapeutic effects while THC is famous for its psychoactive effects that cause feelings of euphoria and sometimes confusion. While CBD and THC have both had plenty of time in the spotlight, lesser-known cannabinoids, such as CBG, are capturing interest from consumers and scientists alike.

Initial studies show that CBG may have similar characteristics of CBD. Both of these cannabinoids have no psychoactive properties. Instead, they offer antioxidant, anti-inflammatory, neuroprotective, and analgesic properties.

Here’s what you need to know about the similarities and differences between CBG and CBD. We’ll also take a look at some of the top CBD products on the market.

What is CBG?

CBG, which stands for cannabigerol, is one of more than 100 cannabinoids found in hemp and cannabis plants. Young hemp plants produce cannabigerolic acid (CBGA). As the plant matures, CBGA breaks down into cannabidiolic acid (CBDA) and tetrahydrocannabinolic acid (THCA). These two compounds are then converted into CBD and THC. Any leftover CBGA is converted into CBG.

Even though CBG was first isolated back in 1964, the cannabinoid didn’t get a lot of attention, so there are very few studies about the compound. Modern research is in preclinical stages, but from what we know so far, CBG may have various therapeutic side effects.

It’s possible that CBG has strong pain-relieving properties that may be more effective than THC. CBG may interact with the CB1 and CB2 receptors of the endocannabinoid system, which influence inflammation, pain, and even heat sensitivity. The cannabinoid may also have antidepressant, anticancer, and antibacterial qualities.

What is CBD?

CBD, which stands for cannabidiol, naturally occurs in high concentrations in hemp and cannabis plants. CBD was first isolated all the way back in the 1930s but was mostly put aside until the 1970s when scientists determined it may be an effective anti-convulsant.

Over the years, research has confirmed many of the therapeutic benefits that CBD offers, including anti-anxiety, pain-relieving, anti-nausea, and sedative qualities. CBD has also shown to be an effective treatment for severe forms of childhood epilepsy and is used in an FDA approved drug, Epidiolex.

Over the last few years, CBD has become the cannabinoid of choice, not only for the many therapeutic benefits it offers, but also because it has no psychoactive properties. Unlike THC, CBD offers pain relief and other benefits without the risk of paranoia, anxiety, or impaired cognitive function.

Like CBG, CBD interacts with the CB1 and CB2 receptors.

Differences Between CBG & CBD

Though they offer very similar therapeutic properties, CBG and CBD do have some differences. For example, the two cannabinoids have different molecular structures. This means that the arrangement of carbon, hydrogen, and oxygen is different. Molecular structure impacts how the cannabinoid binds with receptors and also impacts bioavailability.

CBG and CBD are also unique in how they activate receptors. One study looked at how CBG and CBD interact with the 5-HT1A serotonin receptor . CBG behaves as an antagonist at that receptor, where CBD has strong anti-nausea effects, which means it acts like an agonist.

So even though the two cannabinoids are similar, when bound to the same place, they have opposing effects on this specific receptor.

CBG and CBD differ in how they stimulate the appetite. A study conducted on rats found that CBG encouraged the animals to eat two times their normal food intake. But, a study conducted on CBD found that the cannabinoid significantly reduces total food intake .

Therapeutic Benefits of CBG vs CBD

There isn’t a lot of research that has delved into the therapeutic effects of CBG. However, preclinical studies offer a little bit of insight as to how the cannabinoid may interact with the body. Like CBD, CBG doesn’t have any psychoactive properties. Instead, it offers other therapeutic benefits, including:

● Potential treatment for MRSA bacterial infections

As interest in CBG continues to grow, we can expect to learn more about the cannabinoid over the next few years. The hope is that more clinical studies and research will be conducted so that we can get a better understanding of the benefits that CBG offers.

CBD is in a similar situation, but there are far more studies that have been conducted. Research has found that CBD offers a host of therapeutic benefits, including:

● Lowered stress and anxiety

But as with any cannabinoid, there is always more to learn. Most studies have been conducted on animals, so human trials are crucial to fully understand how CBG and CBD interact in the body.

Are you interested in trying CBD, CBG, or maybe a product that contains both? Here are some of the best hemp-derived products available on the market today.

Top 4 CBD Products

1. Penguin

Penguin is another top brand that we highly recommend. They offer some of the purest and most potent CBD products on the markets. With a well-rounded selection of products, you’re sure to find the CBD that best meets your lifestyle needs. Choose from gummies, oils, topicals, and capsules.

Penguin only uses the best ingredients, including broad-spectrum CBD oil that is extracted from Oregon grown hemp. Because these products contain no THC, you can enjoy peak mental performance while also enjoying the many therapeutic benefits that CBD has to offer.

What’s even better is that the brand offers some delicious flavors. Penguin’s CBD gummy worms are coated in a tangy sugar that will make your taste buds go wild. There’s also deliciously flavored CBD oil, including options such as Cookies & Cream, Citrus, Strawberry, and Mint.

2. Verma Farms

Verma Farms is one of the highest-quality CBD brands that we’ve found. All of their products are made with top notch ingredients that are organic and all natural. They offer an extensive collection of items to choose from, including gummies, oils, capsules, topicals, and even tropical dried fruit!

Verma Farms uses broad spectrum extract, which contains all of the wellness-boosting plant compounds, with the exception of THC. This means you can enjoy the benefits of minor cannabinoids, terpenes, flavonoids, and fatty acids!

This is a brand that takes a Hawaiian approach to making CBD. All of their products are influenced by the islands, so you can drift off to your own tropical paradise.

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3. BATCH CBD

Organically grown and highly effective, BATCH CBD’s products are deeply therapeutic and create lasting benefits for both the body and the mind. Whether you are seeking a better night’s sleep, a way to ease day-to-day stress, or a natural approach to relieve pain and inflammation, BATCH has got you covered.

BATCH CBD prioritizes product quality and customer service to deliver truly life-changing results. From seed to shelf, the BATCH team carefully manages every aspect of their product development, ensuring that each and every product is sustainably crafted with ingredients of the highest quality.

BATCH has an incredible line of CBD products, including their CBG Oil , which includes a 1:1 CBD to CBG ratio . Made with a vegan formula and flavored with citrus extracts, BATCH’s CBG Oil tastes great and offers the substantive benefits of both CBD and CBG!

4. Colorado Botanicals

Colorado Botanicals once again makes our top spot. Despite years of product innovation from its competitors – they stay ahead of the curve with superior quality and some of the most potent CBD oils, capsules, topicals, and gummies on the market.

Initially offering broad-spectrum CBD extracts, Colorado Botanicals recently added full-spectrum CBD oils and several CBG products enhanced with a clinically studied curcumin ingredient and Boswellia. With so much variety and customizability, there’s something for every health-conscious shopper.

Colorado Botanicals is unique in that they can naturally retain terpenes and flavonoids thanks to their proprietary extraction and purification process. The end product is a highly pure and concentrated product without any impurities. Also, their products are constantly tested for contaminants such as heavy metals, pesticides, solvents, and microbes.

5. Extract Labs

Extract Labs is known for providing the purest, highest-quality CBD products at the lowest price, a promise which is made possible by keeping every step of production in-house. Few companies offer CBG products because it is difficult to extract and not as abundant as CBD. Extract Labs offer an extensive collection of CBG products, including full spectrum CBG oil, a THC free CBG tincture, CBG isolate, CBG softgel capsules and CBG gummies. CBG gummies are one of their most popular products, with 33mg CBG and 33mg CBD apiece – they are made with natural ingredients and quality broad spectrum hemp oil. They also have a vast array of high-quality CBD products to try.

6. Joy Organics’ USDA Certified Organic CBG and CBD Tincture

Joy Organics is one of the first CBD oil tinctures on the market to be made entirely of USDA Certified Organic ingredients. This is a brand that doesn’t compromise on quality, using only the highest quality ingredients such as broad and full spectrum CBD, along with organic MCT oil, stevia, and oil-based flavoring.

Joy Organics continues to expand its USDA Certified Organic CBD tinctures with their new CBG and CBD tincture. Their CBG + CBD Tincture contains two hemp-derived compounds to support homeostasis in the body. CBG is known as the “mother of all cannabinoids” and works synergistically with CBD to support mental and physical wellness.

In addition to this tincture, Joy Organics offers a wide array of both full and broad spectrum products that focus on clean and organic ingredients along with extensive lab testing for purity. These products include

Gummies (full and broad spectrum)

Delta 9 products

Final Thoughts

CBD and CBG are two similar yet unique cannabinoids. While hemp plants contain a much higher dose of CBD, CBG can also be extracted and used in all sorts of products. These two cannabinoids offer a variety of therapeutic benefits, and when combined, can provide highly effective relief that keeps you feeling your best.

7 CBG Benefits That’ll Make It The Next Big Thing

While there’s no doubt that CBD has become a hot topic in health and wellness, there’s a new cannabinoid making a notable impression in the scene—CBG.

We’re calling it a “new” cannabinoid, but it’s not technically new. CBG is only now taking center stage in pharmacological studies and making a splash in cannabis product marketing, but CBG is considered a minor cannabinoid with major potential.

In this complete guide to the newest cannabinoid on the block, we’ll get into what researchers are saying about the effects of CBG, what CBG is suitable for, and how to use CBG oil for yourself.

What Does CBG Stand For?

CBG stands for cannabigerol.

Cannabis sativa plants are a natural source of over a hundred phytochemicals known collectively as cannabinoids. To date, most medicinal research focuses primarily on the most abundant cannabinoids, THC (tetrahydrocannabinol) and CBD (cannabidiol), which have both shown incredible, natural health benefits in mammals.

The acidic form of cannabigerol, CBDa (cannabigerol acid), is the parent molecule to better-known cannabinoids —CBDa transforms into THCa and CBDa, essentially the raw, unprocessed forms of THC and CBD.

When dried and heated, a chemical reaction, called decarboxylation, removes the cannabinoid molecule’s carboxylic acids; transforming THCa, CBDa, and CBGa into, THC, CBD, and CBG.

Why Does Hemp Produce Cannabinoids?

It’s amazing how cannabis plants produce so many compounds that interact with the human endocannabinoid system—but why does it produce them in the first place?

It’s believed that cannabinoids protect the cannabis plant from the sun’s harmful UV radiation and harsh climate conditions. Another theory as to why cannabis plants produce cannabinoids is to defend against pests. Many cannabinoids have both anti-bacterial and anti-fungal properties.

A flowering hemp plant begins to produce crystal-like molecules, known as cannabinoids. CBGa emerges around the 3/4-week mark of the flowering phase. As the plant is exposed to ultraviolet radiation from the sun, the CBGa molecule transforms into either THCa, CBGa, or CBCa. This is where the CBG cannabinoid aptly gets its reputation as the parent molecule.

To yield more CBG from the hemp crops, farmers need to harvest their crops before the molecule transforms into other cannabinoids, or hyper-concentrate the small amounts of CBG in full grown hemp plants. However, this harvest will substantially lack THC and CBD levels produced in the later flowering phase.

What Is CBG Good For?

As a cannabinoid, CBG benefits our body’s endocannabinoid system (ECS) and the name “cannabinoid” in the ECS is no coincidence. Its discovery in 1992 came from research looking for how the active compounds in cannabis interact with our bodies.

It turns out these plant-made cannabinoids behave similarly to endogenous (internal) cannabinoids to relay messages within the ECS. The ECS behaves as a modulator for our immune system, nervous system, and nearly all the body’s organs [1].

This explains why THC, CBD, and CBG effects are so extensive. As we’ve briefly mentioned, CBG is the parent molecule to the most notable cannabinoids, THC and CBD. CBG’s importance was once tied strictly to its transformation into these compounds—however, researchers have highlighted CBG’s unique properties and interactions with the endocannabinoid system.

7 CBG Benefits According To Recent Studies

As research progresses in the cannabis space, more and more attention is placed on CBG. It’s important to note that research is still in its early phases, and there’s still a lot to uncover about the benefits of CBG and potential side effects.

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We’ve rounded up the most interesting research to date on the mother of all phytocannabinoids. These findings give insight into what is CBG used for and opens up potential in future research into CBG oil benefits.

1. CBG May Help To Support Focus

Users often report a sense of alertness or focus related to CBG. One of the possible explanations for this effect is that CBG has shown great potential as a neuroprotectant. CBG helps to support healthy inflammatory function and has even been shown to possibly support neurogenesis, the growth of new brain cells—possibly leading to greater capacity for focus and attention.

2. CBG May Help To Support A Healthy Appetite

Marijuana, the cannabis plant potent in the psychoactive compound THC, has been comedically associated with the munchies. CBG seems to share this appetite-stimulating trait with THC. Inducing appetite can help certain people get an adequate amount of nutrients into their bodies.

Overindulging in junk food is typically what comes to mind with the marijuana munchies. However, there are cases in which an increase in appetite is beneficial, such as for those experiencing a lack of appetite for various reasons.

In a study conducted with rats, CBG was found to increase the appetite in well-satiated rats without producing any dangerous side-effects [ 2].

3. CBG May Help To Support A Normal Stress Response

One of the many reasons people turn to hemp-derived CBD oil is to manage their emotional well-being. It turns out that CBG may be more beneficial to help support a normal stress response over its famous counterpart, CBD.

Both CBD and CBG help to inhibit the breakdown of the neurotransmitter, GABA. Increased concentrations of GABA may have potent relaxation effects that help to regulate the stress response [3].

However, there’s another mechanism at play in which CBG helps to support stress management. CBG happens to be a potent 5-HT1A serotonin receptor antagonist [4]. Studies suggest that CBG inhibits serotonin’s uptake, which means a higher concentration of this neurotransmitter may stay active in the brain, helping to support mood [5].

4. CBG May Help to Support Eye Health

There’s a high concentration of cannabinoid receptors in eye tissues. It turns out, the endocannabinoid system may play a vital role in maintaining eye health.

High levels of eye pressure ( ocular hypertension) can result in poor blood flow to the optic nerves, affecting vision. Research suggests that cannabinoids, and notably, CBG, may help to regulate a healthy level of intraocular eye pressure [6].

5. CBG May Help to Support A Normal Inflammatory Response

While CBD is best known for its role in supporting a healthy immune response, CBG has shown effects on particular inflammatory channels in mice related to inflammatory response [7].

According to a recent study, CBG limited the actions of significant inflammatory markers, including IL-1, IL-10, iNOS, and interferon-γ.

The concluding observation in the study found that CBG helped to support a normal inflammatory response.

6. CBG Shows Promise To Support Healthy Metabolic Process

A study published in 2019 supports CBG’s potential in effecting fat storage. Specifically, adipocyte tissues closely related to obesity [8].

This study was conducted via computer simulation, but its positive findings help to progress this research into animal and human studies on CBG and fat metabolism needed to substantiate this benefit.

7. CBG May Help to Support Comfort

One of the more popular reasons people seek out hemp-based products is to help alleviate discomfort naturally.

CBG is found to exhibit more analgesic (comfort-inducing) effects than THC and is a much better GABA reuptake inhibitor than both THC and CBD [9]. Additionally, While we’ve briefly touched on GABA’s effects on the stress response, it’s also a muscle relaxant.

Does CBG Get You High?

A large concern people have when using a cannabis product is its potential for a high feeling. CBG is non-psychoactive and will not get you high. In fact, some research suggests that CBG may work to counteract the psychoactive effects of THC, making it a useful anti-psychotic compound [10].

THC produces a high mainly by activating the CB1 endocannabinoid receptor in the central nervous system. The activated CB1 receptors release a cascade of feel-good hormones, such as serotonin, norepinephrine, and dopamine, associated with high marijuana use.

THC may also interact with serotonin receptors, we mentioned one earlier, 5HT1A. Serotonin has many important jobs, but it plays a vital role in our perceived senses: mood, heart rate, and blood pressure in the central nervous system. CBG counteracts the effects of THC by binding to the CB1 receptors and the 5HT1A receptor.

Aside from producing a high, THC has its own set of health benefits. However, its psychoactive properties make it an undesirable compound for most people—and its legal status remains problematic in most parts of the world. Plant breeders are still looking for ways to include higher concentrations of CBG to high THC marijuana strains to help offset potent psychoactive effects.

Is CBG Legal?

Hemp-derived CBG oil is controlled under the same laws as CBD. As long as the CBG is derived from hemp crops that contain less than 0.3% THC, it’s legal in the United States and Canada. Yet, CBD regulations for sales and purchase may vary state by state and have the potential to change over time. We highly encourage you to always stay engaged and actively follow your local state laws to stay informed.

Because we’re only now beginning to understand CBG benefits, it can be hard to source CBG oil-focused products.

What Is CBG Oil?

The hemp plant is home to a lot of naturally occurring cannabinoids, including one we’re sure you’ve heard of, cannabidiol (CBD). However, the cannabis plant hosts many other minor cannabinoids: CBN, CBG, and Delta-8 THC.

CBG is unique in that it plays a very specific role in the chemistry of cannabis. CBG is the precursor to both THC and CBD. It’s for this reason that total amounts of CBG typically make up less than 1% of the total plant makeup, as it transforms to create other cannabinoids within the plant.

You’ve likely encountered CBG in small amounts in full spectrum CBD oils because the nature of full spectrum extracts is to maintain as much of the natural phytochemical profile of the hemp crops as to produce well-rounded benefits.

In the same way that full spectrum hemp products produce more potent effects over CBD isolate-based products, CBG in full spectrum form is the best form of CBG oil. This is because of a phenomenon called the entourage effect. Plant compounds will yield greater health effects in combination with complementary compounds. Remember, cannabis plants produce over a hundred different cannabinoids that all compound their effects in the ECS.

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While you may see more and more CBG isolate products hitting the market, the best way to add cannabis products into your lifestyle is in a range of cannabinoids either in full spectrum extract or THC-free broad spectrum extracts.

What Are The Side Effects Of CBG?

Now that we have a better understanding of the question, “what does CBG do?” It’s important to look at potential side effects.

There currently aren’t enough clinical trials in humans to determine the potential side effects of CBG. However, CBG, like other cannabinoids, has very low toxicity and it is generally well tolerated. In the clinical trials with rats, where high doses of CBG was used, there were no significant adverse effects [2].

What Are The Main Differences Between CBG and CBD?

Because cannabigerol is the precursor molecule for cannabidiol, there’s no surprise that these cannabinoids have many similarities.

The main differences between the two compounds include:

  • Availability on the market-CBD products are much more abundant
  • CBG is produced in earlier flowering hemp crops
  • CBG is an appetite stimulator while CBD is an inhibitor

What To Look For In A Quality CBG Oil

Responsible Hemp Sourcing

There’s a reason why reputable cannabis brands take so much pride in their hemp sources—a quality product begins at the source.

Nutrient-rich soil, adequate sunlight, and water contribute to the hemp plant’s ability to produce high levels of cannabinoids. Because cannabis plants are so efficient at taking in the nutrients from their surroundings, they’re also susceptible to absorbing harmful contaminants from the environment such as pesticides, heavy metals, and radiation.

Only purchase CBD and CBG oil products from clean, industrial hemp sources.

Third-Party Testing

Unfortunately, trusting that a brand has a quality hemp source isn’t enough. The CBD industry is so new, there isn’t a lot of regulation in place for who can and can’t sell products online. This is where third-party testing comes in to shed some light on business practices.

While this isn’t a mandatory industry practice, third-party lab testing has become a standard. Companies will send a sample of their products to unbiased third-party labs to have it tested for cannabinoid potency and the presence of harmful contaminants.

Checking with the lab testing is a good practice for buying a cannabis-based product.

Final Thoughts: CBG Benefits

Most of the research surrounding the cannabis plant has centered around THC and CBD, as they’re the most abundant compounds. However, there are over a hundred more minor cannabinoids that contribute to the many health benefits of hemp extracts that are worth looking into.

As the parent molecule to many different cannabinoids and its non-psychoactive effects, CBG stands out as the next big compound. You’ll likely be seeing more of it the health and wellness space as more selective breeding, early crop harvesting, and CBG isolation become more popular.

As for shopping for any health-related product, you should always do your due diligence when it comes to research as not all cannabis products are made equal. To make sure you’re getting safe and effective CBD and CBG oils, shop from reputable brands, check where the hemp is sourced, and reference third-party lab testing.

If you’ve tried CBG before, let us know what you think in the comment section below.

What is CBG?

CBG stands for cannabigerol. It’s one of the many non-psychoactive minor cannabinoids found in cannabis plants. CBG has the nickname “the parent molecule” because its raw form, cannabigerolic acid, is the precursor to CBD and THC.

What is CBG Good for?

CThe research on CBG is still new, but it shows a lot of promise for supporting brain health, normal inflammation, and relief from discomfort. It shares many of the same benefits as CBD, but with an emphasis on focus and alertness, making it ideal for daytime use.

Does CBG Get You High?

CBG is not considered a psychoactive cannabinoid and does not produce intoxicating effects like THC does—the main psychoactive cannabinoid in marijuana.

How Does CBG Make You Feel?

CBG can affect individuals differently depending on their experience with cannabinoids, genetics, and lifestyle. Many people report feeling more focused, alert, and a sense of calm when taking CBG products, which is why it’s become a favorite tool for productivity.

Resources:
  1. Alger, B. E. (2013, November). Getting high on the endocannabinoid system. In Cerebrum: the Dana forum on brain science (Vol. 2013). Dana Foundation.
  2. Brierley, D. I., Samuels, J., Duncan, M., Whalley, B. J., & Williams, C. M. (2016). Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats. Psychopharmacology, 233(19), 3603-3613.
  3. Banerjee, S. P., Snyder, S. H., & Mechoulam, R. A. P. H. A. E. L. (1975). Cannabinoids: influence on neurotransmitter uptake in rat brain synaptosomes. Journal of Pharmacology and Experimental Therapeutics, 194(1), 74-81.
  4. Bantick, R. A., Rabiner, E. A., Hirani, E., de Vries, M. H., Hume, S. P., & Grasby, P. M. (2004). Occupancy of agonist drugs at the 5-HT1A receptor. Neuropsychopharmacology, 29(5), 847-859.
  5. Cascio, M. G., Gauson, L. A., Stevenson, L. A., Ross, R. A., & Pertwee, R. G. (2010). Evidence that the plant cannabinoid cannabigerol is a highly potent α2‐adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. British journal of pharmacology, 159(1), 129-141.
  6. Nadolska, K., & Goś, R. (2008). Possibilities of applying cannabinoids’ in the treatment of glaucoma. Klinika Oczna, 110(7-9), 314-317.
  7. Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., . & Izzo, A. A. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical pharmacology, 85(9), 1306-1316.
  8. D’Aniello, E., Fellous, T., Iannotti, F. A., Gentile, A., Allarà, M., Balestrieri, F., . & Di Marzo, V. (2019). Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach. Biochimica et Biophysica Acta (BBA)-General Subjects, 1863(3), 586-597.
  9. International cannabinoid research society. (2004). 14th Annual Symposium on the Cannabinoids: Ariston Hotel, Paestum, Italy, June 22-27, 2004: Program and Abstracts. international cannabinoid research Society, Department of psychology, University of Vermont.
  10. Cascio, M. G., Gauson, L. A., Stevenson, L. A., Ross, R. A., & Pertwee, R. G. (2010). Evidence that the plant cannabinoid cannabigerol is a highly potent α2‐adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. British journal of pharmacology, 159(1), 129-141.
Disclaimer

The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product.

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