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Learn everything there is to know about THC tinctures. Find out what they are, how you can make them, and how to dose and use them at Leafly. You hear a lot of confusing cannabis acronyms, and probably wonder: what the heck do they all mean and why do there need to be so many? This article breaks down THC and CBD and how they can be used together.

Cannabis tinctures 101: How to make, consume, and dose them

In the landscape of cannabis innovations, including rosin vape pens, transdermal topicals, and nanotechnology beverages, tried-and-true classic products can get overlooked.

One of the first innovations in plant medicine, with documentation as far back as 1025 in The Al-Qanoon fi al Tibb, aka, The Canon of Medicine, was the tincture. In the millennium since, there have been innumerable innovations, but we’re here to say that good weed and a good product never go out of style.

What is a cannabis tincture?

A tincture in the most basic sense is a cannabis extract, in which a liquid is infused with cannabis, meant for sublingual consumption, not vaporization or smoking. The cannabis plant soaks in a base liquid, such as food-grade alcohol, glycerin, or even oil, and after days of steeping, the plant matter is strained out and—voilà! The cannabinoids, terpenes, and other compounds have melded with the base liquid, ready to dose and consume.

Technically, the term “tincture” specifically refers to an alcohol-based product and one made with oil or glycerin is an “infusion,” but we’re using it as an umbrella term here.

In the adult-use market, tinctures typically come in 1 fl oz (30mL) glass bottles with droppers to administer low and consistent doses. Because they are not considered a food item, they can exceed the 100 mg THC cap on edibles in many markets.

Tinctures may not seem as fun or innovative as a gummy or a dab, but they have a multitude of health benefits while still offering a comfortable, intoxicating experience.

Tincture vs. edibles

While both tinctures and edibles require ingestion to work, they enter the bloodstream via different bodily systems and will have distinct effects.

Edibles require digestion and are processed in the stomach and liver, and enzymes in the liver enhance the effects of ingested THC. Tinctures do not pass through the liver and are absorbed under the tongue, so while the high will be more immediate, it won’t be as strong.

How does a tincture compare to CBD oil?

CBD oils sold in wellness stores and online bear a strong resemblance to tinctures, but the two differ significantly in some areas.

Namely, a CBD oil not sold in a licensed adult-use or medical marijuana dispensary is typically produced by isolating and extracting CBD from hemp using a solvent, like butane or CO2, and then binding the extract to a carrier oil.

Tinctures are whole plant extracts and even when extracted from compliant hemp plants, they may contain trace amounts of THC.

Additionally, because tinctures are often alcohol-based, they cannot be used as a topical or skin-conditioning product the way CBD oil can. Both, however, can be taken orally to yield CBD’s therapeutic benefits.

Benefits of using cannabis tinctures

While they may not seem as edgy as other consumption methods, tinctures have endured in apothecaries and dispensaries for centuries because they are considered one of the healthiest ways to consume cannabis.

No food allergens or sensitive ingredients

Some brands flavor or enhance tinctures, but you only need the cannabis plant and the base to which it is bound. This means sugar, gluten, gelatin, food coloring, and any other ingredients that may aggravate intolerances or allergies can be avoided.

Discretion

Tinctures at a glance resemble a skincare product or wellness supplement. If sealed, they don’t stink like buds, and they don’t produce smoke or vapor that as with inhalation methods.

Flexible dosing

Tinctures are not beholden to the 100mg edible cap in many markets, so one bottle will last you a lot longer than a tin of gummies or a brownie. You can also control your dose, down to the drop.

Fast-acting

If taken sublingually, tinctures’ effects have a speedier onset than eating an edible, since they absorb through the tissue in the mouth (though it will take a little longer than smoking). This also means tinctures last longer than smoking a joint, but may metabolize faster than an edible made with fats, like baked goods.

Full spectrum

Since tinctures involve soaking the entire cannabis plant, consumers get a myriad of benefits from all the compounds in the plant beyond just THC and/or CBD.

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THC tincture dosage guide

This is based on a 300 mg THC, 1 fl oz (30 mL) tincture.

Dosage in ml Approximate dose in mg Effects
0.10 ml 3 mg Microdose for very low intoxication
0.25 ml 7.5 mg Light dose with low intoxication for beginners and sensitive consumers
0.50 ml 15 mg Standard dose with slight intoxication
1 ml 30 mg Higher than average dose for experienced consumers
2 ml 60 mg Potent dose for experienced consumers or patients with serious ailments

How to use or take cannabis tinctures

Cannabis companies operating in legal markets are required by law to include accurate dosing information for ingestible products. If you pick up a tincture from your local dispensary, it will have dosing information on the packaging. Most health and CBD stores also provide this, but THC-free tinctures don’t always go through the same degree of testing.

Your ideal dose will depend on your tolerance, as well as the goal of taking the tincture. If the tincture has been formulated for helping with sleep, you may want a single high dose to ensure sedation. If you intend to use the tincture for general daytime wellness, you may find that multiple microdoses throughout the day may achieve a more uplifting experience.

Rule of thumb, as with anything weed-related, start low and go slow. In a 1 fl oz bottle, one full dropper equates to 1 mL, so we advise starting with a quarter dropper or less if you have a low tolerance or do not regularly consume high amounts of cannabis. You can go for half a dropper if you feel more confident.

For maximum efficacy, use the dropper to deposit the tincture under the tongue, and let it sit for 30 seconds before swallowing.

The mouth has absorbent tissue called oral mucosa, essentially a mucous membrane that lines the inside of cheeks, lips, and under the tongue that helps fight disease and keeps our mouths healthy. It also absorbs tinctures and administers cannabinoids into the bloodstream directly, without going through the stomach or liver.

How long does it take for a cannabis tincture to kick in?

Tinctures typically take effect within 15-30 minutes if left to sit under the tongue for 30-45 seconds. Swallowing a tincture directly can compromise its efficacy as your body won’t absorb it the way it will an edible or food item. Tinctures mixed with food will take longer to take effect, but may yield a more potent high.

Can you cook with tinctures?

Cooking with tinctures depends primarily on the formulation and how you plan to incorporate it into cooking. Since most tinctures contain THC, CBD and/or other cannabinoids that have been decarboxylated, exposing the tincture to high heat via an oven, stove, or boiling water may burn them away, rendering the final food useless from a medicinal standpoint.

However, you can easily add a tincture to the finished dish by incorporating it in a sauce or dressing. They also make good additions to top up cannabis weed tea recipes.

How to make cannabis tinctures

Tinctures are one of the easiest cannabis products to make at home. They require almost little equipment and you don’t need a high level of plant science, but they do need patience.

The ratio of base to flower will determine how concentrated the tincture is. A tincture made from an ounce of cannabis, for example, should be steeped in about 25 fl oz of base liquid for mild doses once in a 1 fl oz bottle. For a more potent tincture, use less of the base liquid or more weed.

Ingredients

  • Eighth to a half ounce (3.5 – 14 grams) cannabis flower
  • 3 – 12 fl oz. food-grade ethanol, glycerin or a carrier oil, such as coconut oil

Equipment

  • Glass mason jars
  • Coffee filters or a cheesecloth
  • A 1 fl oz glass bottle and dropper cap

Directions

Step 1

Decarboxylate your cannabis. Because no heat is involved in the tincture-making process, you’ll need to activate your buds if you want an intoxicating effect from THC. You’ll need a baking tray, parchment paper, and flower.

Your cannabis should be ground and/or broken down for maximum surface area. Set your oven to between 220-240ºF (going too high will burn away cannabinoids) and lay the cannabis flower on the parchment paper on the tray. Let bake for 30 minutes to no more than an hour—any longer will cook all the good stuff away.

You can leave the plant raw if you prefer to harness the non-intoxicating benefits of THCA and CBDA, the acidic forms of THC and CBD. You may see better results if you grind the bud beforehand.

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Step 2

Pour your base and cannabis into a mason jar at your desired ratio; an eighth of cannabis to 3 fl oz solvent yields a fairly mellow and buildable dose. Cut the base amount or increase flower amount by ⅓ for a more potent effect; there needs to be enough of your base for the cannabis to be totally submerged. Stir the contents well.

Step 3

Store your tincture mixture in a cool dry place for at least four weeks, shaking and/or stirring once a day. This agitation helps the base liquid better soak into the flower.

Step 4

Over time, the plant’s cannabinoids and terpenes will dissolve (alcohol) or infuse (glycerin) with the base. A longer steep time will yield a more potent tincture.

Strain the mixture through a coffee filter or cheesecloth to remove all plant matter. What you’ll be left with is a dark liquid full of weedy goodness, ready to dose.

Freeze method

Maybe you don’t have weeks to spare to wait for a tincture to infuse, or you don’t like waiting. Here is an alternative recipe that you can do in a day.

Like in ice water hashmaking, freezing the bud before infusion, but after decarboxylation, helps dislodge the cannabinoid-rich trichomes from the plant. This recipe requires the use of alcohol as your tincture’s base.

Step 1

Decarb your cannabis (see above).

Step 2

Freeze the alcohol and cannabis in separate mason jars overnight. This makes the trichomes more brittle and will help the tincture taste less like plant matter.

Step 3

Mix the alcohol and bud in one mason jar. Seal and shake it for one minute.

Step 4

Place the mason jar mixture back in the freezer for five minutes to ensure contents stay cold and frozen.

Step 5

Repeat the shaking of step 3 and step 4 two more times.

Step 6

Strain the mixture through a filter of your choice to separate plant matter.

Step 7

Bottle your tincture and enjoy!

Alcohol, glycerin, oil: Which is the best base?

Historically, tinctures have been made using an alcohol base. Alcohol cuts through the lipids and plant matter in the cannabis plant so the terpenes and cannabinoids dissolve into it.

Alcohol also helps the tincture enter the bloodstream more efficiently compared to glycerin or another oil.

Keep in mind that when we say alcohol, we don’t mean cocktails or the kind of alcohol you use to clean your bongs. One of the most popular options by far is Everclear, a grain alcohol with proofs as high as 190.

Glycerin-based tinctures will be less potent because glycerin—a sugar alcohol often derived from plant oils, like coconut or soybean—doesn’t bind to cannabinoids as well as an ethanol alcohol. Don’t worry, you’ll still reap many of the tincture’s benefits. Glycerin has a sweeter taste than alcohol and won’t irritate your mouth if you have any oral sensitivities.

Oil-based tinctures are ideal if you want a low, manageable dose, but they bind the least efficiently to cannabis compounds. The upside is that if the tincture isn’t to your liking, you can still use it as a skincare and topical product.

This article was originally published June 16, 2016 and is often updated for accuracy and clarity.

How to Use THC and CBD Together

You hear a lot of confusing cannabis acronyms, and probably wonder: what the heck do they all mean and why do there need to be so many? THC is one you probably know, and CBD too. THC and CBD are both phytocannabinoids, and they are found in the cannabis plant. There are over 100 known cannabinoids, with researchers believing there are more that have been yet to be discovered. THC and CBD are among the most popular, and you’ll probably hear them being talked about the most.

You might know THC as the cannabinoid responsible for getting you high, and you’d be correct! THC works by binding to the CB1 receptors found in the endocannabinoid system. The endocannabinoid system is a bodily system every human being has, and even every animal!

The endocannabinoid system

It might sound like pseudoscience, but trust us, the endocannabinoid system is very well-documented. UCLA, for example, has an entire initiative dedicated to cannabinoid research. The endocannabinoid system was discovered decades ago, and researchers believe its primary purpose is to help regulate the body and bring it to a place of homeostasis. CBD also interacts with the body’s endocannabinoid system, but in a more roundabout way. Instead of binding directly to either receptor, CBD works mainly by regulating inflammation in the body.

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Mixing CBD and THC

Let’s talk about mixing CBD and THC. Many people wonder if this is okay, or something people do. Think about it like this: THC and CBD already co-exist together in the cannabis plant, and in literally every joint/bowl/etc you’ve ever smoked! If you’ve consumed a high-THC cannabis product, smoking or not, you’ve mixed CBD and THC. Cannabis is naturally riddled with cannabinoids, both THC and CBD. So when you consume cannabis, you’re already mixing CBD and THC!

So to simplify the answer, yes. Mixing CBD and THC products is perfectly fine, great even, because of something known as the entourage effect. The entourage effect is the idea that cannabinoids work better together, instead of apart. Since hemp-derived CBD joined the legal marketplace, we hear a lot about something called full-spectrum CBD. Full-spectrum CBD is simply a hemp-derived CBD product with a full cannabinoid and terpene profile. It’s the idea of using the entire plant, instead of just isolating bits and pieces of it.

Full-spectrum profiles have both THC and CBD

In a full-spectrum profile, you should be able to find potent concentrations of CBD, CBN, and CBC. There should be THC present too, but the amount depends on whether or not the product is hemp-derived or derived from high-THC cannabis. You’ll also find CBD isolate extracts, which basically means the product is CBD alone, without THC or other plant compounds present.

A little about terpenes

Terpenes will also be found in a full-spectrum profile, and terpenes are responsible for the way cannabis smells and tastes. The most popular terpenes include:

  • Linalool
  • Limonene
  • B-caryophyllene
  • Myrcene

Terpenes are thought to have some pretty powerful benefits of their own, like anti-inflammatory and antiseptic properties. You won’t find any additional cannabinoids or terpenes, and there are many experts who think CBD isolate should be removed completely. We believe some cannabinoids are better than none, but we also support the idea behind the entourage effect. What could be better than the whole plant?

The entourage effect

Let’s talk a little more about the entourage effect. When you consume cannabinoids together, your body will better utilize them. The cannabinoids interact in such a way that creates balance in your body. Most of the entourage effect research we have available is exploring the use of THC and CBD specifically.

Dr. Ethan Russo is one of the biggest supporters of the entourage effect, and he even wrote an insightful review making a case for the phenomenon. This review highlighted different pieces of evidence to support the entourage effect (sometimes called cannabis synergy), and mentioned how CBD and CBG were shown to be effective against fighting MRSA, a bacterial skin infection. Mixing your CBD and THC might give you more powerful results than you could have thought possible, though we don’t have conclusive evidence.

CBD can negate some of THC’s effects

Have you ever had too much THC? If you have, you know it isn’t an enjoyable experience. Your heart might race, you’ll probably feel anxious and paranoid. An unexpected benefit of the entourage effect is CBD’s ability to cancel THC. If you have too much THC, take some CBD and wait a few minutes. You should start to feel the high come down! This is a great trick for new consumers, and even seasoned consumers who have had a little too much. This is the entourage effect at work, too, just in a different way!

Save time, track your consumption

This is why tracking your consumption is important. The Farmer’s Wife is launching a patient journal that allows medical marijuana consumers to keep track of how much medicine they’re currently taking. You can write about your emotional and physical state, as well as exactly which product you consumed and how much. This way, you always have a written reference as to how much you need. Dosing your medicine can be challenging, especially if you notice it frequently fluctuates. Keeping track of how you feel can be a great way to identify some potential triggers, and do what you can to reduce them. For example, you might not respond to a certain product each and every time, but the same product with a little bit higher THC content is your go-to. We can’t possibly be expected to remember how we feel at every turn, which is where journaling comes in handy.

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