Can I Take CBD Oil And St John’s Wort Together

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Is it fine to take St. John’s wort with cannabidiol (CBD) Cannabis? I am taking 25 mg CBD hemp oil for 3 days now and I am on 900 mg of St Johns Wort for depression. Im taking CBD for insomnia WebMD provides information about interactions between St. John’s Wort and antipsychotics-sibutramine.

Is it fine to take St. John’s wort with cannabidiol (CBD) Cannabis?

I am taking 25 mg CBD hemp oil for 3 days now and I am on 900 mg of St Johns Wort for depression. Im taking CBD for insomnia and relief from arthritis. I feel great for about 3 hours and then get a slight headache. I am not sure if this is due to an interaction between the CBD and St Johns Wort but would like to learn more.

So you have been taking the CBD for 3 days? How long have you been taking the st. john’s wort? I know from personal experience that st john’s can cause heachaches. Also CBD effects Cannabinoid receptors in the brain which is different than st john’s because it effects the serotonin receptors. I don’t think an interaction is likely but if anyone has any other info about this then I am all ears. Hope this helped.
P.S. Try buying a St John’s wort tincture, and break your dose into 500mg (.5ml) in the morning and at night. See where that takes you.

Cannabidiol; Tetrahydrocannabinol/Strong CYP3A4 Inducers Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

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Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Your medicine may speed up how quickly your liver processes cannabidiol (CBD) and tetrahydrocannabinol (THC).

What might happen:

Your blood levels of CBD and THC may decrease and they may not work as well.

What you should do about this interaction:

Let your healthcare professional (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change or adjust the dose of one of your medicines.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.

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